THE MOLECULAR IMPASSE OF EVOLUTION

Left-handed Proteins

Let us now examine in detail why the evolutionist scenario regarding the formation of proteins is impossible.

Even the correct sequence of the right amino acids is still not enough for the formation of a functional protein molecule. In addition to these requirements, each of the 20 different types of amino acids present in the composition of proteins must be left-handed. There are two different types of amino acids-as of all organic molecules-called "left-handed" and "right-handed". The difference between them is the mirror-symmetry between their three dimensional structures, which is similar to that of a person's right and left hands.

Amino acids of either of these two types can easily bond with one another. But one astonishing fact that has been revealed by research is that all the proteins in plants and animals on this planet, from the simplest organism to the most complex, are made up of left-handed amino acids. If even a single right-handed amino acid gets attached to the structure of a protein, the protein is rendered useless. In a series of experiments, surprisingly, bacteria that were exposed to right-handed amino acids immediately destroyed them. In some cases, they produced usable left-handed amino acids from the fractured components.

Let us for an instant suppose that life came about by chance as evolutionists claim it did. In this case, the right- and left-handed amino acids that were generated by chance should be present in roughly equal proportions in nature. Therefore, all living things should have both right- and left-handed amino acids in their constitution, because chemically it is possible for amino acids of both types to combine with each other. However, as we know, in the real world the proteins existing in all living organisms are made up only of left-handed amino acids.

The question of how proteins can pick out only the left-handed ones from among all amino acids, and how not even a single right-handed amino acid gets involved in the life process, is a problem that still baffles evolutionists. Such a specific and conscious selection constitutes one of the greatest impasses facing the theory of evolution.

Moreover, this characteristic of proteins makes the problem facing evolutionists with respect to "coincidence" even worse. In order for a "meaningful" protein to be generated, it is not enough for the amino acids to be present in a particular number and sequence, and to be combined together in the right three-dimensional design. Additionally, all these amino acids have to be left-handed: not even one of them can be right-handed. Yet there is no natural selection mechanism which can identify that a right-handed amino acid has been added to the sequence and recognise that it must therefore be removed from the chain. This situation once more eliminates for good the possibility of coincidence and chance.

The Brittanica Science Encyclopaedia, which is an outspoken defender of evolution, states that the amino acids of all the living organisms on earth, and the building blocks of complex polymers such as proteins, have the same left-handed asymmetry. It adds that this is tantamount to tossing a coin a million times and always getting heads. The same encyclopaedia states that it is impossible to understand why molecules become left-handed or right-handed, and that this choice is fascinatingly related to the origin of life on earth.113

If a coin always turns up heads when tossed a million times, is it more logical to attribute that to chance, or else to accept that there is conscious intervention going on? The answer should be obvious. However, obvious though it may be, evolutionists still take refuge in coincidence, simply because they do not want to accept the existence of "conscious intervention".

A situation similar to the left-handedness of amino acids also exists with respect to nucleotides, the smallest units of the nucleic acids, DNA and RNA. In contrast to proteins, in which only left-handed amino acids are chosen, in the case of the nucleic acids, the preferred forms of their nucleotide components are always right-handed. This is another fact that can never be explained by coincidence.

In conclusion, it is proven beyond a shadow of doubt by the probabilities we have examined that the origin of life cannot be explained by chance. If we attempt to calculate the probability of an average-sized protein consisting of 400 amino acids being selected only from left-handed amino acids, we come up with a probability of 1 in 2400, or 10120. Just for a comparison, let us remember that the number of electrons in the universe is estimated at 1079, which although vast, is a much smaller number. The probability of these amino acids forming the required sequence and functional form would generate much larger numbers. If we add these probabilities to each other, and if we go on to work out the probabilities of even higher numbers and types of proteins, the calculations become inconceivable.


Correct Bond is Vital

The difficulties the theory of evolution is unable to overcome with regard to the development of a single protein are not limited to those we have recounted so far. It is not enough for amino acids to be arranged in the correct numbers, sequences, and required three-dimensional structures. The formation of a protein also requires that amino acid molecules with more than one arm be linked to each other only in certain ways. Such a bond is called a "peptide bond". Amino acids can make different bonds with each other; but proteins are made up of those-and only those-amino acids which are joined by "peptide" bonds.

A comparison will clarify this point. Suppose that all the parts of a car were complete and correctly assembled, with the sole exception that one of the wheels was fastened in place not with the usual nuts and bolts, but with a piece of wire, in such a way that its hub faced the ground. It would be impossible for such a car to move even the shortest distance, no matter how complex its technology or how powerful its engine. At first glance, everything would seem to be in the right place, but the faulty attachment of even one wheel would make the entire car useless. In the same way, in a protein molecule the joining of even one amino acid to another with a bond other than a peptide bond would make the entire molecule useless.

Research has shown that amino acids combining at random combine with a peptide bond only 50% of the time, and that the rest of the time different bonds that are not present in proteins emerge. To function properly, each amino acid making up a protein must be joined to others only with a peptide bond, in the same way that it likewise must be chosen only from among left-handed forms.

This probability of this happening is the same as the probability of each protein's being left-handed. That is, when we consider a protein made up of 400 amino acids, the probability of all amino acids combining among themselves with only peptide bonds is 1 in 2399.


Zero Probability

As can be seen below, the probability of formation of a protein molecule made up of 500 amino acids is "1" over a number formed by placing 950 zeros next to 1, which is a number incomprehensible for the human mind. This is a probability only on paper. Practically speaking, there is zero chance of its actually happening. As we saw earlier, in mathematics, a probability smaller than 1 in 1050 is statistically considered to have a "0" probability of occurring.

A probability of "1 over 10950" is far beyond the limits of this definition.

While the improbability of the formation of a protein molecule made up of 500 amino acids reaches such an extent, we can further proceed to push the limits of the mind with higher levels of improbability. In the "haemoglobin" molecule, which is a vital protein, there are 574 amino acids, which is more than the amino acids making up the protein mentioned above. Now consider this: in only one out of the billions of red blood cells in your body, there are "280,000,000" (280 million) haemoglobin molecules.

The supposed age of the earth is not sufficient to allow the formation of even a single protein by a "trial and error" method, let alone that of a red blood cell. Even if we suppose that amino acids have combined and decomposed by a "trial and error" method without losing any time since the formation of the earth, in order to form a single protein molecule, the time that would be required for something with a probability of 10950 to happen would still hugely exceed the estimated age of the earth.

The conclusion to be drawn from all this is that evolution falls into a terrible abyss of improbability even when it comes to the formation of a single protein.


Is There a Trial and Error Mechanism in Nature?

Finally, we may conclude with a very important point in relation to the basic logic of probability calculations, of which we have already seen some examples. We indicated that the probability calculations made above reach astronomical levels, and that these astronomical odds have no chance of actually happening. However, there is a much more important and damaging fact facing evolutionists here. This is that under natural conditions, no period of trial and error can even start, despite the astronomical odds, because there is no trial-and-error mechanism in nature from which proteins could emerge.

The calculations we give on page across to demonstrate the probability of the formation of a protein molecule with 500 amino acids are valid only for an ideal trial-and-error environment, which does not actually exist in real life. That is, the probability of obtaining a useful protein is "1" in 10950 only if we suppose that there exists an imaginary mechanism in which an invisible hand joins 500 amino acids at random and then, seeing that this is not the right combination, disentangles them one by one, and arranges them again in a different order, and so on. In each trial, the amino acids would have to be separated one by one, and be arranged in a new order. The synthesis should be stopped after the 500th amino acid has been added, and it must be ensured that not even one extra amino acid is involved. The trial should then be stopped to see whether or not a functional protein has yet been formed, and, in the event of failure, everything should be split up again and then tested for another sequence. Additionally, in each trial, not even one extraneous substance should be allowed to become involved. It is also imperative that the chain formed during the trial should not be separated and destroyed before reaching the 499th link. These conditions mean that the probabilities we have mentioned above can only operate in a controlled environment where there is a conscious mechanism directing the beginning, the end, and each intermediate stage of the process, and where only "the correct selection of the amino acids" is left uncontrolled. It is clearly impossible for such an environment to exist under natural conditions. Therefore the formation of a protein in the natural environment is logically and technically impossible. In fact, to talk of the probabilities of such an event is quite unscientific.

Zero Probability
There are 3 basic conditions for the formation of a useful protein:

First condition: that all the amino acids in the protein chain are of the right type and in the right sequence

Second condition: that all the amino acids in the chain are left-handed

Third condition: that all of these amino acids are united between them by forming a chemical bond called "peptide bond".

In order for a protein to be formed by chance, all three basic conditions must exist simultaneously. The probability of the formation of a protein by chance is equal to the multiplication of the probabilities of the realisation of each of these conditions.

For instance, for an average molecule comprising of 500 amino acids:

1. The probability of the amino acids being in the right sequence:

There are 20 types of amino acids used in the composition of proteins. According to this:
-The probability of each amino acid being chosen correctly among these 20 types = 1/20
-The probability of all of those 500 amino acids being chosen correctly = 1/20500= 1/10650
  = 1 chance in 10650

2. The probability of the amino acids being left-handed:

-The probability of only one amino acid being left-handed = 1/2
-The probability of all of those 500 amino acids being left-handed at the same time = 1/2500  =  1/10150
= 1 chance in 10150

3. The probability of the amino acids being combined with a "peptide bond":

Amino acids can combine with each other with different kinds of chemical bonds. In order for a useful protein to be formed, all the amino acids in the chain must have been combined with a special chemical bond called a "peptide bond". It is calculated that the probability of the amino acids being combined not with another chemical bond but by a peptide bond is 50%. In relation to this:

-The probability of two amino acids being combined with a "peptide bond" = 1/2
-The probability of 500 amino acids all combining with peptide bonds = 1/2499  = 1/10150
  = 1 chance in 10150

 
TOTAL PROBABILITY = 1/10650 X 1/10150 X 1/10150 = 10950
= 1 chance in 10950

 

The probability of an average protein molecule made up of 500 amino acids being arranged in the correct quantity and sequence in addition to the probability of all of the amino acids it contains being only left-handed and being combined with only peptide bonds is "1" over 10950. We can write this number which is formed by putting 950 zeros next to 1 as follows:

10950 =

100.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000. 
000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000. 
000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000. 
000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000. 
000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000. 
000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000. 
000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000. 
000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000. 
000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000. 
000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000. 
000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000. 
000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000. 
000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000. 
000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000. 
000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000. 
000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000.000. 
000.000.000.000.000.000.000.000.000.000.000.000.000.

Since some people are unable to take a broad view of these matters, but approach them from a superficial viewpoint and assume protein formation to be a simple chemical reaction, they may make unrealistic deductions such as "amino acids combine by way of reaction and then form proteins". However, accidental chemical reactions taking place in an inanimate structure can only lead to simple and primitive changes. The number of these is predetermined and limited. For a somewhat more complex chemical material, huge factories, chemical plants, and laboratories have to be involved. Medicines and many other chemical materials that we use in our daily life are made in just this way. Proteins have much more complex structures than these chemicals produced by industry. Therefore, it is impossible for proteins, each of which is a wonder of creation, in which every part takes its place in a fixed order, to originate as a result of haphazard chemical reactions.

Let us for a minute put aside all the impossibilities we have described so far, and suppose that a useful protein molecule still evolved spontaneously "by accident". Even so, evolution again has no answers, because in order for this protein to survive, it would need to be isolated from its natural habitat and be protected under very special conditions. Otherwise, it would either disintegrate from exposure to natural conditions on earth, or else join with other acids, amino acids, or chemical compounds, thereby losing its particular properties and turning into a totally different and useless substance.

113 Fabbri Britannica Bilim Ansiklopedisi (Fabbri Britannica Science Encyclopaedia), vol 2, No 22, p. 519.